Article

Engineered human myogenic cells in hydrogels generate functional myofibers within dystrophic mouse muscle

2023-09-05

Abstract excerpt

Transplantation of human myogenic progenitor cells (MPCs) is a promising therapeutic strategy for treating muscle-wasting diseases, e.g., Duchenne muscular dystrophy (DMD). To increase engraftment efficiency of donor stem cells, modulation of host muscles is required, significantly limiting their clinical translation. Here we develop a clinically relevant transplantation strategy synergising hydrogel-mediated deli...

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Literature Corpus work: 5f3b99f6-b960-5f31-91f6-8896169cf5fd
DOI: 10.1101/2023.09.05.556335

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