Article

Autism Polygenic Score Is Associated With Sex-Dependent Broadening of Brain Network Variability

2026-08-25

Abstract excerpt

<h4>Background: </h4> Autism polygenic scores (PGS) reliably predict case-control status yet explain little variance in autism-related traits. Landscape accounts of neurodevelopmental diversity propose that genetic liability broadens the range of viable neural configurations rather than shifting brain organisation toward dysfunction. We tested whether autism polygenic load is associated with increased variability...

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Literature Corpus work: 5ee773de-b709-5a5e-a7d7-3a4942454368
DOI: 10.64898/2026.08.18.745469

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