Article
Enteroids: Promising in Vitro Models for Studies of Intestinal Physiology and Nutrition in Farm Animals
11 Feb 2019
Abstract excerpt
The lack of sophisticated in vitro models limits our current understanding of gastrointestinal functions in farm animals. Conventional 2D cell lines or primary cells fail to recapitulate the physiology of in vivo intestinal epithelium. In contrast stem cell-derived, nontransformed 3D enteroids partially recreate the villus-crypt anatomy of the native intestine and comprise most if not all intestinal cell types...
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