Article

Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation

2024-10-13

Abstract excerpt

Flaviviruses replicate their genomes in replication organelles (ROs) formed as bud-like invaginations on the endoplasmic reticulum (ER) membrane, which also functions as the site for virion assembly. While this localization is well established, it is not known to what extent viral membrane remodeling, genome replication, virion assembly, and maturation are coordinated. Here, we imaged tick-borne flavivirus replica...

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Literature Corpus work: 5e7e0d99-8ff5-5f4c-9e0f-9bf4a6301d40
DOI: 10.1101/2024.10.13.618056

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