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Cryo-electron tomography reveals lineage-specific replication features of Zika virus

2025-08-18

Abstract excerpt

Zika virus (ZIKV), a member of the Flavivirus genus, can cause severe neurodevelopmental disorders when infection occurs during pregnancy. Phylogenetic analyses classify ZIKV into two major lineages: African and Asian. Despite their genetic similarity, only the Asian lineage has been linked to congenital anomalies. ZIKV possesses a single-stranded RNA genome and replicates by remodelling the host endoplasmic retic...

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Literature Corpus work
e264025f-846b-5f56-8e87-6b27763e8304
DOI
10.1101/2025.08.15.670067
Open publication

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Cryo-electron tomography reveals lineage-specific replication features of Zika virusDOI 10.1101/2025.08.15.670067
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