Article

Molecular mechanisms of altered gastrointestinal function in gastrin deficient mice

2001-01-01

Abstract excerpt

The peptide hormone gastrin is synthesized and secreted by G-cells in the antral region of the stomach. Well characterised functions of gastrin include stimulation of gastric acid secretion and gastric mucosal proliferation. More recent studies in gastrin deficient transgenic mice (GAS-KO) suggest that gastrin also regulates corpus epithelial architecture. Gastrin regulated genes mediate acid secretion and prolife...

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Literature Corpus work: 5e6fa4ca-f111-5550-b55c-49c7acff1672
DOI: 10.17638/03167615

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