Article
Transcription factor foxq1 controls mucin gene expression and granule content in mouse stomach surface mucous cells.
Gastroenterology - 1 Aug 2008
Verzi Michael P, Khan Abdul H, Ito Susumu, Shivdasani Ramesh A
Abstract excerpt
BACKGROUND & AIMS: The gastric mucosa provides a stringent epithelial barrier and produces acid and enzymes that initiate digestion. In this regenerating tissue, progenitors differentiate continually into 4 principal specialized cell types, yet underlying mechanisms of differentiation are poorly understood. We identified stomach-restricted expression of the forkhead transcription factor FOXQ1. METHODS: We used a...
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