Article

Three-dimensional models of the cervicovaginal epithelia to study host-microbiome interactions and sexually transmitted infections

2021-11-05

Abstract excerpt

<h4>ABSTRACT</h4> Two-dimensional (2D) cell culture systems have provided controlled, reproducible means to analyze host-pathogen interactions. Although inexpensive, straightforward, and requiring very short time commitment, these models recapitulate neither the functionality of multi-layered cell types nor the microbial diversity of an infected human. Animal models have commonly been used to recreate the complex...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5e5c4600-8f23-5d44-857c-322ceb87c481
DOI: 10.1101/2021.11.04.467382

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Three-dimensional models of the cervicovaginal epithelia to study host-microbiome interactions and sexually transmitted infectionsDOI 10.1101/2021.11.04.467382Read

Three-dimensional models of the cervicovaginal epithelia to study host–microbiome interactions and sexually transmitted infectionsSemantic proximity Read

Human Three-Dimensional Endometrial Epithelial Cell Model To Study Host Interactions with Vaginal Bacteria and Neisseria gonorrhoeae.Semantic proximity Read

Tissue Models for Neisseria gonorrhoeae Research—From 2D to 3DSemantic proximity Read

Mucus production, host-microbiome interactions, hormone sensitivity, and innate immune responses modeled in human cervix chipsSemantic proximity Read

Single-cell atlas of patient-derived cervical organoids uncovers epithelial immune heterogeneity and intercellular crosstalk during Chlamydia infectionSemantic proximity Read

Effects of Female Sex Hormones on Susceptibility to HSV-2 in Vaginal Cells Grown in Air-Liquid InterfaceSemantic proximity Read

Modeling Host-Pathogen Interactions in the Context of the Microenvironment: Three-Dimensional Cell Culture Comes of AgeSemantic proximity Read

The Establishment of 3D Polarity-Reversed Organoids From Human Endometrial Tissue as a Model for Infection-Induced EndometritisSemantic proximity Read

Human Cervix Chip: A Preclinical Model for Studying the Role of the Cervical Mucosa and Microbiome in Female Reproductive HealthSemantic proximity Read

3D Oral and Cervical Tissue Models for Studying Papillomavirus Host‐Pathogen InteractionsSemantic proximity Read

A renewed tool kit to explore Chlamydia pathogenesis: from molecular genetics to new infection modelsSemantic proximity Read

Growing Role of 3D In Vitro Cell Cultures in the Study of Cellular and Molecular Mechanisms: Short Focus on Breast Cancer, Endometriosis, Liver and Infectious DiseasesSemantic proximity Read