Article

Taxonomic-free metagenome GWAS to identify gut microbiome functions influencing host phenotypes

2026-01-15

Abstract excerpt

Genome-wide association studies (GWAS) have been pivotal for uncovering the genetics of human phenotypes, and there is now growing interest in applying GWAS-like methods to explore the role of the microbiome in human health. Here, we developed a taxonomy free GWAS approach that uses k-mers, i.e. DNA words of length k that can capture single nucleotide polymorphisms, insertion or deletion events, and gene presence-...

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Literature Corpus work: 5e292dd9-84ba-5bbc-8eb2-92d72d0d66d0
DOI: 10.64898/2026.01.15.699651

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