Article
Bacterial SNPs in the human gut microbiome associate with host BMI.
Nature medicine - 1 Nov 2023
Zahavi Liron, Lavon Amit, Reicher Lee, Shoer Saar, Godneva Anastasia, Leviatan Sigal, Rein Michal, Weissbrod Omer, Weinberger Adina, Segal Eran
Abstract excerpt
Genome-wide association studies (GWASs) have provided numerous associations between human single-nucleotide polymorphisms (SNPs) and health traits. Likewise, metagenome-wide association studies (MWASs) between bacterial SNPs and human traits can suggest mechanistic links, but very few such studies have been done thus far. In this study, we devised an MWAS framework to detect SNPs and associate them with host...
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