Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analgesia and Opioids: A Pharmacogenetics Shortlist for Implementation in Clinical Practice.

Clinical chemistry - 1 Jul 2017

Matic Maja, de Wildt Saskia N, Tibboel Dick, van Schaik Ron H N

Abstract excerpt

BACKGROUND: The use of opioids to alleviate pain is complicated by the risk of severe adverse events and the large variability in dose requirements. Pharmacogenetics (PGx) could possibly be used to tailor pain medication based on an individual's genetic background. Many potential genetic markers have been described, and the importance of genetic predisposition in opioid efficacy and toxicity has been demonstrated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analgesics, Opioid
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to OPRM1 gene

Share to Genetic Variation

Share to Glucuronosyltransferase

Share to Pain Management

Share to Pharmacogenetics

Source

Identifiers

PMID: 28637770
DOI: 10.1373/clinchem.2016.264986

Genes

ABCB1
ABCC3
COMT
KCNJ6
OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analgesia and Opioids: A Pharmacogenetics Shortlist for Implementation in Clinical Practice.PMID 28637770Read ↗

Reviewing pharmacogenetics to advance precision medicine for opioidsSemantic proximity Read ↗

Pain polymorphisms and opioids: An evidence based reviewSemantic proximity Read ↗

Pain and genetics.Semantic proximity Read ↗

Fundamental Considerations for GeneticallyGuided Pain Management with Opioids Based on CYP2D6 and OPRM1 PolymorphismsSemantic proximity Read ↗

A Review of the Role of Genetic Testing in Pain MedicineSemantic proximity Read ↗

Review of Opioid Pharmacogenetics and Considerations for Pain ManagementSemantic proximity Read ↗

Pharmacogenomics of opioids and perioperative pain management.Semantic proximity Read ↗

Pain management in the 21st century: utilization of pharmacogenomics and therapeutic drug monitoring.Semantic proximity Read ↗

Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6, OPRM1, and COMT Genotypes and Select Opioid Therapy.Semantic proximity Read ↗

Analysis Approaches to Identify Pharmacogenetic Associations With Pharmacodynamics.Semantic proximity Read ↗

Genetics and Opioids: Towards More Appropriate Prescription in Cancer PainSemantic proximity Read ↗

Role of pharmacogenetics in variable response to drugs: focus on opioidsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.