Article

Antibiotic treatment modestly reduces protection against Mycobacterium tuberculosis reinfection in macaques

2023-12-19

Abstract excerpt

Concomitant immunity is generally defined as an ongoing infection providing protection against reinfection 1 . Its role in prevention of tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is supported by epidemiological evidence in humans as well as experimental evidence in mice and non-human primates (NHPs). Whether the presence of live Mtb, rather than simply persistent antigen, is necessary for conc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5dde37b6-3073-5c7e-8113-abb7675f0d5a
DOI: 10.1101/2023.12.19.570845

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Antibiotic treatment modestly reduces protection against Mycobacterium tuberculosis reinfection in macaquesDOI 10.1101/2023.12.19.570845Read

Concurrent TB and HIV therapies effectively control clinical reactivation of TB during co-infection but fail to eliminate chronic immune activationSemantic proximity Read

PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaquesSemantic proximity Read

Impact of aging on the immunological and microbial landscape of the lung during non-tuberculous mycobacterial infectionSemantic proximity Read

Protection against reinfection with <i>Mycobacterium tuberculosis</i> extends across heterologous Mtb lineagesSemantic proximity Read

Understanding nontuberculous mycobacterial lung disease: it’s been a long time comingSemantic proximity Read

Protective intravenous BCG vaccination induces enhanced immune signaling in the airwaysSemantic proximity Read

Intervening along the spectrum of tuberculosis: meeting report from the World TB Day nanosymposium in the Institute of Infectious Disease and Molecular Medicine at the University of Cape TownSemantic proximity Read

Control of Mycobacterium tuberculosis Infection in Lungs is Associated with Recruitment of Antigen-Specific Th1 and Th17 cells Co-expressing CXCR3 and CCR6Semantic proximity Read

The population dynamics and control of tuberculosis.Semantic proximity Read

Diversity of Human and Macaque Airway Immune Cells at Baseline and during Tuberculosis Infection.Semantic proximity Read

Exposure to <i>mycobacterium</i> remodels alveolar macrophages and the early innate response to <i>Mycobacterium tuberculosis</i> infectionSemantic proximity Read

Host Immune Response to Mycobacterium tuberculosis Infection: Implications for Vaccine DevelopmentSemantic proximity Read