Diversity of Human and Macaque Airway Immune Cells at Baseline and during Tuberculosis Infection.

doi:10.1165/rcmb.2016-0122OC

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Diversity of Human and Macaque Airway Immune Cells at Baseline and during Tuberculosis Infection.

American journal of respiratory cell and molecular biology - 1 Dec 2016

Silver Richard F, Myers Amy J, Jarvela Jessica, Flynn JoAnne, Rutledge Tara, Bonfield Tracey, Lin Philana Ling

Abstract excerpt

Immune cells of the distal airways serve as "first responders" of host immunity to the airborne pathogen Mycobacterium tuberculosis (Mtb). Mtb infection of cynomolgus macaques recapitulates the range of human outcomes from clinically silent latent tuberculosis infection (LTBI) to active tuberculosis of various degrees of severity. To further advance the application of this model to human studies, we compared...

Topics

Adolescent
Adult
Animals
Biomarkers
Bronchoalveolar Lavage Fluid
Humans
Latent Tuberculosis
Leukocyte Count
Leukocytes
Lung
Lymphocyte Subsets

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Macaca fascicularis

Middle Aged

Mycobacterium tuberculosis

Phagocytes

Phenotype

Tuberculosis, Pulmonary

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 27509488
DOI: 10.1165/rcmb.2016-0122OC
PMCID: PMC5248955

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diversity of Human and Macaque Airway Immune Cells at Baseline and during Tuberculosis Infection.PMID 27509488Read ↗

Differences in Host Immune Populations Between Rhesus Macaques and Cynomolgus Macaque Subspecies, in Relation to Susceptibility to Mycobacterium Tuberculosis Infection.Semantic proximity Read ↗

Cutting Edge: Characterization of Human Tissue-Resident Memory T Cells at Different Infection Sites in Patients with Tuberculosis.Semantic proximity Read ↗

Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune Cells.Semantic proximity Read ↗

B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles.Semantic proximity Read ↗

PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaquesSemantic proximity Read ↗

B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and putative functional rolesSemantic proximity Read ↗

Control of Mycobacterium tuberculosis Infection in Lungs is Associated with Recruitment of Antigen-Specific Th1 and Th17 cells Co-expressing CXCR3 and CCR6Semantic proximity Read ↗

Beyond the Clinic: The Activation of Diverse Cellular and Humoral Factors Shapes the Immunological Status of Patients with Active TuberculosisSemantic proximity Read ↗

Disease progression is associated with differential neutrophil maturation in <i>Mycobacterium tuberculosis-infected</i> macaquesSemantic proximity Read ↗

Airway immune signatures of protection and disease progression in recent human tuberculosis household contactsSemantic proximity Read ↗

The double‐edged sword of Tregs in M tuberculosis, M avium, and M. abscessus infectionSemantic proximity Read ↗

Host Immune Response to Mycobacterium tuberculosis Infection: Implications for Vaccine DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.