Article

Discovery of indole-modified aptamers for highly specific recognition of protein glycoforms

2021-03-14

Abstract excerpt

Glycosylation is one of the most abundant forms of post-translational modification, and can have a profound impact on a wide range of biological processes and diseases. Unfortunately, efforts to characterize such modifications in the context of basic and clinical research are severely hampered by the lack of affinity reagents that can differentiate protein glycoforms. This lack of reagents is largely due to the ch...

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Literature Corpus work: 5ddb766a-8c32-5fbf-bf1b-e3832a7814da
DOI: 10.1101/2021.03.13.435263

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