Article

<i>TRIM71</i> deficiency causes germ cell loss during mouse embryogenesis and promotes human male infertility

2021-02-02

Abstract excerpt

Mutations affecting the germline can result in infertility or the generation of germ cell tumors (GCT), highlighting the need to identify and characterize the genes controlling the complex molecular network orchestrating germ cell development. TRIM71 is a stem cell-specific factor essential for embryogenesis, and its expression has been reported in GCT and adult mouse testes. To investigate the role of TRIM71 in m...

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Literature Corpus work: 5dd9f2b4-55fe-51ce-8e40-0f9f59c41ccf
DOI: 10.1101/2021.02.01.429172

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