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Boldo Restores Vascularization and Reduces Inflammation of Skeletal Muscle in Symptomatic Mice with Dysferlinopathy

2025-08-18

Abstract excerpt

Dysferlinopathies are progressive muscular dystrophies caused by mutations in the DYSF gene, leading to defective membrane repair, chronic inflammation, lipid accu-mulation, and muscle degeneration. No approved therapies currently halt disease progression. This study evaluated the effects of daily oral administration of pulverized Boldo (Peumus boldus) leaves, a nutraceutical with reported bioactive properties, in...

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Identifiers and source

Literature Corpus work
5dc647f7-7342-5838-abfe-b9fc93f7adbb
DOI
10.20944/preprints202508.1188.v1
Open publication

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Boldo Restores Vascularization and Reduces Inflammation of Skeletal Muscle in Symptomatic Mice with DysferlinopathyDOI 10.20944/preprints202508.1188.v1
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