Article

Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function

2021-04-30

Abstract excerpt

<h4>ABSTRACT</h4> Microsatellite expansions of CCTG repeats in the CNBP gene leads to accumulation of toxic RNA and have been associated to DM2. However, it is still unclear whether the dystrophic phenotype is also linked to CNBP decrease, a conserved CCHC-type zinc finger RNA binding protein that regulates translation and is required for mammalian development. Here we show that depletion of Drosophila CNBP in m...

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Literature Corpus work: 5daa0e97-43ff-5add-84bb-274c997acb8f
DOI: 10.1101/2021.04.29.441910

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