Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function

Abstract excerpt

Microsatellite expansions of CCTG repeats in the cellular nucleic acid-binding protein ( CNBP ) gene leads to accumulation of toxic RNA and have been associated with myotonic dystrophy type 2 (DM2). However, it is still unclear whether the dystrophic phenotype is also linked to CNBP decrease, a conserved CCHC-type zinc finger RNA-binding protein that regulates translation and is required for mammalian...

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