Metaproteomics Reveals Potential Mechanisms by which Dietary Resistant Starch Supplementation Attenuates Chronic Kidney Disease Progression in Rats

Abstract excerpt

<h4>Background</h4> Resistant starch is a prebiotic metabolized by the gut bacteria. It has been shown to attenuate chronic kidney disease (CKD) progression in rats. Previous studies employed taxonomic analysis using 16S rRNA sequencing and untargeted metabolomics profiling. Here we expand these studies by metaproteomics, gaining new insight into the host-microbiome interaction. <h4>Methods</h4> Differences betw...

Topics

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• Clostridium difficile and Clostridium perfringens research
• Dialysis and Renal Disease Management
• Diet and metabolism studies
• Food composition and properties
• Gut microbiota and health
• Metabolomics and Mass Spectrometry Studies
• Probiotics and Fermented Foods

Identifiers and source

Literature Corpus work

5d7c5d05-9718-5f4b-835d-cd23577066e4

DOI

10.1101/340513