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Gut flora metagenomic analysis coupled with metabolic and deep immune profiling in chronic kidney disease

18 Jan 2024

Abstract excerpt

BACKGROUND: Perturbation of gut microbiota has been linked to chronic kidney disease (CKD), which was correlated with a sophisticated milieu of metabolic and immune dysregulation. METHODS: To clarify the underlying host-microbe interaction in CKD, we performed multi-omics measurements, including systems-level gut microbiome, targeted serum metabolome and deep immunotyping, in a cohort of patients and non-CKD...

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PMID: 38244232
DOI: 10.1093/ndt/gfae013

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