Article

Chronic diazepam reveals excessive homeostatic gain in SOD1 <sup>G93A</sup> mouse spinal motoneurons

2026-05-19

Abstract excerpt

Motoneurons are under strong pressure to maintain stable motor output throughout an individual life, through homeostatic regulation of their electrical properties. Dysregulated spinal motoneuron excitability has long been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS). Recent work in SOD1 G93A mice suggests that the homeostatic response of motoneurons becomes dysregulated as cellular proces...

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Literature Corpus work: 5d687c86-9941-56d7-9276-db01720f06ff
DOI: 10.64898/2026.05.16.725609

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