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Spatial and temporal coordination of Duox/TrpA1/Dh31 and IMD pathways is required for the efficient elimination of pathogenic bacteria in the intestine of <i>Drosophila</i> larvae

2024-01-27

Abstract excerpt

Multiple gut antimicrobial mechanisms are coordinated in space and time to efficiently fight foodborne pathogens. In Drosophila melanogaster , production of reactive oxygen species (ROS) and antimicrobial peptides (AMPs) together with intestinal cell renewal play a key role in eliminating gut microbes. A complementary mechanism would be to isolate and treat pathogenic bacteria while allowing colonization by comme...

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Identifiers and source

Literature Corpus work
5d62f043-be19-5b99-a3d7-7f6215644556
DOI
10.1101/2024.01.26.577406
Open publication

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Spatial and temporal coordination of Duox/TrpA1/Dh31 and IMD pathways is required for the efficient elimination of pathogenic bacteria in the intestine of <i>Drosophila</i> larvaeDOI 10.1101/2024.01.26.577406
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