Article

Drosophila melanogaster mitigates gastro-oral infections by stimulating pathogen expulsion

2026-01-13

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Food-borne pathogens, particularly belonging to the <italic>Enterobacteriaceae</italic> family, are a major cause of gastrointestinal infections in humans. While <italic>Drosophila melanogaster</italic> has been widely explored to study antimicrobial responses, most studies rely on septic injury or direct injection, routes that bypass the gut. A coordinate...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1206d770-b9f2-596d-a0c4-be13c6bb356c
DOI: 10.21203/rs.3.rs-8473557/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Drosophila melanogaster mitigates gastro-oral infections by stimulating pathogen expulsionDOI 10.21203/rs.3.rs-8473557/v1Read

Spatial and temporal coordination of Duox/TrpA1/Dh31 and IMD pathways is required for the efficient elimination of pathogenic bacteria in the intestine of <i>Drosophila</i> larvaeSemantic proximity Read

ROS-dependent innate immune mechanisms control <i>Staphylococcus aureus</i> MRSA virulence in the <i>Drosophila</i> larval modelSemantic proximity Read

Lipopolysaccharide-mediated resistance to host antimicrobial peptides and hemocyte-derived reactive-oxygen species are the major <i>Providencia alcalifaciens</i> virulence factors in <i>Drosophila melanogaster</i>Semantic proximity Read

<i>Drosophila</i> as a model system to unravel the layers of innate immunity to infectionSemantic proximity Read

Colonization of larval zebrafish ( <i>Danio rer</i> io) with adherent-invasive <i>Escherichia coli</i> prevents recovery of the intestinal mucosa from drug-induced colitisSemantic proximity Read

Unexpected role of the IMD pathway in Drosophila gut defense against Staphylococcus aureusSemantic proximity Read

Human pathogenic bacteria, fungi, and viruses inDrosophilaSemantic proximity Read

Pathogen-Induced Damage in Drosophila: Uncoupling Disease Tolerance from ResistanceSemantic proximity Read

Pathogenic fungi-induced susceptibility is mitigated by mutual Lactobacillus plantarum in the Drosophila melanogaster modelSemantic proximity Read

High sugar diets can increase susceptibility to bacterial infection in <i>Drosophila melanogaster</i>Semantic proximity Read

Antibiotic alters host’s gut microbiota, fertility and antimicrobial peptide gene expression vis-à-vis ampicillin treatment on model organism Drosophila melanogasterSemantic proximity Read

Enteric bacterial infection in <i>Drosophila</i> induces whole-body alterations in metabolic gene expression independently of the Immune Deficiency (Imd) signalling pathwaySemantic proximity Read