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Article

Isolation and characterization of a clade 2.3.4.4b genotype D1.1 H5N1 virus from dairy cattle in Wisconsin.

Journal of virology - 18 Aug 2026

Mezhenskaia Daria, Babujee Lavanya, Lim Ailam, Guan Lizheng, Nguyen Dani, Gu Chunyang, Neumann Gabriele, Poulsen Keith, Eisfeld Amie J, Kawaoka Yoshihiro

Abstract excerpt

Highly pathogenic avian influenza A(H5N1) (HPAI H5N1) viruses of clade 2.3.4.4b have recently been detected in U.S. dairy cattle following multiple spillover events from avian reservoirs. In December 2025, HPAI H5N1 virus was identified in a dairy herd in Wisconsin through the National Milk Testing Strategy. Here, we report the isolation of a clade 2.3.4.4b, genotype D1.1 H5N1 virus, A/dairy...

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Cattle
Cattle Diseases
Influenza A Virus, H5N1 Subtype
Mice
Milk

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Orthomyxoviridae Infections

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Identifiers

PMID: 42429628
DOI: 10.1128/jvi.00761-26
PMCID: PMC13483294

Genes

F2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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