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Avian influenza A (H5N1) virus in dairy cattle: origin, evolution, and cross-species transmission

13 Nov 2024

Abstract excerpt

Since the emergence of highly pathogenic avian influenza virus (HPAIV) H5N1 of clade 2.3.4.4b as a novel reassortant virus from subtype H5N8, the virus has led to a massive number of outbreaks worldwide in wild and domestic birds. Compared to the parental HPAIV H5N8 clade 2.3.4.4b, the novel reassortant HPAIV H5N1 displayed an increased ability to escape species barriers and infect multiple mammalian species,...

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PMID: 39535188
DOI: 10.1128/mbio.02542-24

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