Article

miR-186 Regulates the Initiation and Development of Breast Cancer via SHP-1 Methylation

2020-08-31

Abstract excerpt

<title>Abstract</title> <bold>Background </bold>Change in the methylation status of genomic DNA, especially in CpG islands in the promoter region, is considered to be an early event in tumor initiation, leading to silencing of gene expression, subsequent abnormalities in gene structure and function, and malignant transformation of the cell. Due to the abnormal expression of miR-186 and SHP-1 in breast cancer t...

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Literature Corpus work: 5cef0828-cf22-5c87-a912-7d697914ad79
DOI: 10.21203/rs.3.rs-58916/v1

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