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Article

DNA methylation of <i>RASSF1A, HIN‐1, RAR‐β, Cyclin D2</i> and <i>Twist</i> in <i>in situ</i> and invasive lobular breast carcinoma

18 Sept 2003

Abstract excerpt

Little is known about epigenetic silencing of genes by promoter hypermethylation in lobular breast cancers. The promoter methylation status of 5 cancer-related genes (RASSF1A, HIN-1, RAR-beta, Cyclin D2 and Twist) was evaluated in 2 types of lobular cancers, in situ (LCIS) and invasive lobular carcinomas (ILC) (n = 32), and compared to ductal in situ (DCIS) and invasive (IDC) breast cancers (n = 71). By using...

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PMID: 14601057
DOI: 10.1002/ijc.11508

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