Article

Genome wide association study of clinical duration and age at onset of sporadic CJD

2023-10-17

Abstract excerpt

Human prion diseases are rare, transmissible and often rapidly progressive dementias. The most common type, sporadic Creutzfeldt-Jakob disease (sCJD), is highly variable in clinical duration and age at onset. Genetic determinants of late onset or slower progression might suggest new targets for research and therapeutics. We assembled and array genotyped sCJD cases diagnosed in life or at autopsy. Clinical duration...

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Literature Corpus work: 5c762d40-444e-5f9c-84c1-cbea6c0dacdd
DOI: 10.1101/2023.10.17.23297050

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