Article
Genome-wide association study of behavioural and psychiatric features in human prion disease.
Translational psychiatry - 21 Apr 2015
Thompson A G B, Uphill J, Lowe J, Porter M-C, Lukic A, Carswell C, Rudge P, MacKay A, Collinge J, Mead S
Abstract excerpt
Prion diseases are rare neurodegenerative conditions causing highly variable clinical syndromes, which often include prominent neuropsychiatric symptoms. We have recently carried out a clinical study of behavioural and psychiatric symptoms in a large prospective cohort of patients with prion disease in the United Kingdom, allowing us to operationalise specific behavioural/psychiatric phenotypes as traits in human...
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