Article

Regulation of the unfolded protein response transducer IRE1α by SERPINH1 aggravates periodontitis with diabetes mellitus via prolonged ER stress

2021-09-20

Abstract excerpt

<title>Abstract</title> <p>Background The hyperglycemic microenvironment induced by diabetes mellitus aggravates the inflammatory response, in which the inositol-requiring enzyme-1α (IRE1α) signal transduction pathway of the unfolded protein response (UPR) participates. This study aimed to investigate the mechanism by which hyperglycemia regulates the IRE1α signaling pathway and affects endoplasmic reticulum (ER...

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Literature Corpus work: 5bfbe010-a53c-536c-9e2a-52ab6d5461b2
DOI: 10.21203/rs.3.rs-895678/v1

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Regulation of the unfolded protein response transducer IRE1α by SERPINH1 aggravates periodontitis with diabetes mellitus via prolonged ER stressDOI 10.21203/rs.3.rs-895678/v1Read

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