Article

Interplay of Systemic Diseases and Genetic Factors in Peri-Implantitis: Integrative Transcriptomic and Clinical Evidence from Patients with Diabetes, Hypertension, and Osteoporosis

2026-04-23

Abstract excerpt

<title>Abstract</title> <p> Background: Peri-implantitis (PI) is a significant cause of dental implant failure and is characterized by inflammatory destruction of peri-implant tissues with progressive bone loss. Increasing evidence indicates that systemic conditions such as diabetes mellitus (DM), hypertension (HTN), and osteoporosis (OP) may exacerbate peri-implant inflammation by affecting immune regulation a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 99463890-3cdc-57a1-97ae-107cee925060
DOI: 10.21203/rs.3.rs-9325336/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Interplay of Systemic Diseases and Genetic Factors in Peri-Implantitis: Integrative Transcriptomic and Clinical Evidence from Patients with Diabetes, Hypertension, and OsteoporosisDOI 10.21203/rs.3.rs-9325336/v1Read

The Molecular Comorbidity Network of Periodontal DiseaseSemantic proximity Read

Integrative analysis of ferroptosis-related genes and immune infiltration in peri-implantitisSemantic proximity Read

Single-Cell Transcriptome Atlas of the Canine Peri-implantitis Reveals stromal–immune cells interactionSemantic proximity Read

Impact of periodontitis on type 2 diabetes: a bioinformatic analysisSemantic proximity Read

Single-cell transcriptomics reveal micro-environment alterations in canine peri-implantitisSemantic proximity Read

Identification of Novel Genome-Wide Associations for Oral Inflammatory TraitsSemantic proximity Read

Molecular Signature of Peri-Implantitis: An AI-Driven Transcriptomic Analysis Reveals a Foreign-Body Inflammatory Phenotype; A Pilot StudySemantic proximity Read

The role of inflammation and genetics in periodontal diseaseSemantic proximity Read

Genetic variants associated with systemic inflammatory disease associate with temporomandibular symptoms with or without periodontitis.Semantic proximity Read

The underlying molecular mechanisms and biomarkers between periodontitis and COVID- 19Semantic proximity Read

Deciphering Periodontitis: Host Mechanisms, Predictive Biomarkers, and Systemic Drivers for Precision PreventionSemantic proximity Read

Overlapping genetic, immune, and inflammatory mechanisms in periodontitis and autoimmune rheumatic diseases: implications for biomarker discovery and treatment.Semantic proximity Read