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Characterization of β-secretase inhibitory extracts from sea cucumber (Stichopus japonicus) hydrolysis with their cellular level mechanism in SH-SY5Y cells

2021-08-01

Abstract excerpt

Alzheimer’s disease (AD) is the main type of dementia found in the elderly population. The prevention of β-amyloid (Aβ) production by inhibiting β-secretase, which is required for Aβ generation, is the major focus of research in AD therapeutics. In this study, enzymatic extracts obtained from sea cucumber (Stichopus japonicus) hydrolysis were investigated for β-secretase inhibitory activities. Sea cucumber hydroly...

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Literature Corpus work
5bfa6680-2095-5193-8bb5-6aff1fa9819b
DOI
10.1007/s00217-021-03770-6
Open publication

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