Article

Rapacaspase-9-based Suicide Gene Applied to the Safety of Il-1rap Car-t Cells

2022-11-14

Abstract excerpt

<title>Abstract</title> <p>Even if adoptive cell transfer (ACT) has already shown great clinical efficiency in different types of disease, such as cancer, some adverse events consistently occur, and suicide genes are an interesting system to manage these events. Our team developed a new medical drug candidate, a chimeric antigen receptor (CAR) targeting interleukin-1 receptor accessory protein (IL-1RAP), which ne...

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Literature Corpus work: 5bc96001-6088-51ef-afe3-9054ea5dff95
DOI: 10.21203/rs.3.rs-2246139/v1

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