Article

Lead-Induced Molecular Alterations and Symplekins’ Role in Tight Junction Dynamics: Implications for Cancer

2024-12-18

Abstract excerpt

The mechanisms underlying the connection between exposure to lead and cancer are not completely understood. Lead is thought to cause oxidative stress, impair DNA repair pathways, and contribute to inflammation, potentially increasing carcinogenesis. The involvement of the Symplekin in cancer biology induced by lead exposure is an emerging area of research. Symplekin is a crucial protein in RNA processing and polya...

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Literature Corpus work: 5b9f895f-2fa3-50e0-9b72-9a4f8a1d4eab
DOI: 10.22541/au.173450720.02125594/v1

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