Article

Bisphenol A promotes stress granule assembly and modulates the integrated stress response

2019-06-17

Abstract excerpt

Bisphenol-A (BPA) is a ubiquitous precursor of polycarbonate plastics that is found in the blood and serum of >92% of Americans. While BPA has been well documented to act as a weak estrogen receptor (ER) agonist, its effects on cellular stress are unclear. Here, we demonstrate that high-dose BPA causes stress granules (SGs) in human cells. A common estrogen derivative, β-estradiol, does not trigger SGs, indicating...

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Literature Corpus work: 526b1d63-9f30-51be-9320-6cf61e9ce968
DOI: 10.1101/673194

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