Article
Long Non-Coding RNAs: A Novel Paradigm for Toxicology.
Toxicological sciences : an official journal of the Society of Toxicology - 1 Jan 2017
Dempsey Joseph L, Cui Julia Yue
Abstract excerpt
Long non-coding RNAs (lncRNAs) are over 200 nucleotides in length and are transcribed from the mammalian genome in a tissue-specific and developmentally regulated pattern. There is growing recognition that lncRNAs are novel biomarkers and/or key regulators of toxicological responses in humans and animal models. Lacking protein-coding capacity, the numerous types of lncRNAs possess a myriad of transcriptional...
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