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Retained introns in phototransduction genes of 5xFAD mouse retina suggest vision impairment as an early diagnostic marker for Alzheimer’s disease

2025-05-08

Abstract excerpt

<title>Abstract</title> <p>Alzheimer’s disease (AD) is an age-related neurodegenerative disorder characterized by neuronal and synaptic loss in the brain, which leads to cognitive impairment and dementia. Therefore, early diagnosis by employing various biomarkers is crucial for preventing and treating AD. Although retinal pathology is an emerging biomarker associated with AD, detailed molecular mechanisms of reti...

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Literature Corpus work
5b9b2912-77ff-5cdf-9ff9-085c2eb544d4
DOI
10.21203/rs.3.rs-6392160/v1
Open publication

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Retained introns in phototransduction genes of 5xFAD mouse retina suggest vision impairment as an early diagnostic marker for Alzheimer’s diseaseDOI 10.21203/rs.3.rs-6392160/v1
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