Article
Characterization of a dominant cone degeneration in a green fluorescent protein-reporter mouse with disruption of Loci associated with human dominant retinal dystrophy.
Investigative ophthalmology & visual science - 22 Aug 2011
Lipinski Daniel M, Yusuf Mohammed, Barnard Alun R, Damant Christopher, Charbel Issa Peter, Singh Mandeep S, Lee Edward, Davies Wayne L, Volpi Emanuela V, MacLaren Robert E
Abstract excerpt
PURPOSE. To characterize anatomically and functionally the retinal degeneration observed in a transgenic mouse line (OPN1LW-EGFP) expressing enhanced green fluorescent protein (EGFP) in a subpopulation of cone photoreceptors, and to map the location of the transgenic insertion. METHODS. An anatomic comparison of cone survival was carried out between wild type (WT) and transgenic mice at three postnatal time...
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