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Therapeutic Potential of <em>Lappula patula</em> Extracts on Germline Development and DNA Damage Responses in <em>C. elegans</em>

2025-01-08

Abstract excerpt

Lappula patula extracts exhibit significant nematocidal activity, germline disruption, and DNA damage responses in C. elegans. Exposure to increasing concentrations of L. patula extract led to a dose-dependent reduction in worm survival and development, without affecting the high incidence of male phenotype. Further investigation revealed pronounced germline defects, including increased nuclear spacing in the prem...

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Literature Corpus work
5b7e3bfe-1782-5356-bef3-53e58e12e43d
DOI
10.20944/preprints202501.0572.v1
Open publication

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