Article

The molecular charaterisation of the Tylosis with Oesophageal Cancer (TOC) minimal region sequence

2003-01-01

Abstract excerpt

Tylosis is a benign autosomal dominantly inherited disorder of the skin that manifests as focal thickening of the palmar and plantar surfaces. The disorder is associated with the early onset of squamous cell oesophageal cancer in two large families from the UK and US and a smaller German pedigree. The familial cancer association is rare in the general population, but the gene is also implicated in the development...

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Literature Corpus work: 5b6dd266-adef-510a-b63b-24bcd8564723
DOI: 10.17638/03167684

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