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Article

Genetic steps in the development of squamous cell carcinoma of the esophagus.

Mutation research - 1 Apr 2000

Mandard A M, Hainaut P, Hollstein M

Abstract excerpt

Esophageal squamous cell carcinoma (ESCC) is a frequent form of cancer that shows striking variations in geographic distribution, reflecting exposure to specific environmental factors that are still poorly defined. ESCC develops as the result of a sequence of histopathological changes that typically involves esophagitis, atrophy, mild to severe dysplasia, carcinoma in situ and finally, invasive cancer. Genetic...

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Source

Identifiers

PMID: 10767643
DOI: 10.1016/s1383-5742(00)00019-3

Genes

EGFR
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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