Aerobic exercise during exposure to 40Hz light flicker protects against early cognitive impairments in Alzheimer’s disease of 3xTg mice

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Alzheimer’s disease (AD) is a progressive degenerative brain disease and the primary cause of dementia. At an early stage, AD is generally characterized by memory impairment involving recent experiences owing to dysfunctions of the cortex and hippocampus. The lesion gradually spreads to the association cortex. Early amyloid-β (Aβ) deposition and tau protein expr...

Topics

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• Acoustic Stimulation
• Conditioning, Operant
• Dark Adaptation
• Excitatory Postsynaptic Potentials
• Exploratory Behavior
• Maze Learning
• Neural Inhibition
• Reflex, Startle

Identifiers and source

Literature Corpus work

5b59176b-e7c2-599b-b46d-197183adda25

DOI

10.21203/rs.3.rs-100200/v1