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Cytogenetics and genomics in CML and other myeloproliferative neoplasms.

Best practice & research. Clinical haematology - 1 Jun 2024

Kreipe Hans H, Schlegelberger Brigitte

Abstract excerpt

Chronic myeloid leukemia is defined by the presence of the Philadelphia translocation t (9; 22) resulting in the BCR::ABL1 fusion. The other myeloproliferative neoplasms (MPN) subtypes also carry typical chromosomal abnormalities, which however are not pathognomonic for a specific entity of MPN. According to the WHO classification the distinction between these entities is still based on the integration of...

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Calreticulin
Chromosome Aberrations
Fusion Proteins, bcr-abl
Janus Kinase 2
Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Myeloproliferative Disorders

Receptors, Thrombopoietin

Translocation, Genetic

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Identifiers

PMID: 39098796
DOI: 10.1016/j.beha.2024.101552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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