Article
Cytogenetics and genomics in CML and other myeloproliferative neoplasms.
Best practice & research. Clinical haematology - 1 Jun 2024
Kreipe Hans H, Schlegelberger Brigitte
Abstract excerpt
Chronic myeloid leukemia is defined by the presence of the Philadelphia translocation t (9; 22) resulting in the BCR::ABL1 fusion. The other myeloproliferative neoplasms (MPN) subtypes also carry typical chromosomal abnormalities, which however are not pathognomonic for a specific entity of MPN. According to the WHO classification the distinction between these entities is still based on the integration of...
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