Article

KIF24 depletion induces Fe–S-dependent mitochondrial dysfunction and AMPK/p53/SLC7A11 mediated ferroptosis in gastric cancer

2026-07-14

Abstract excerpt

<title>Abstract</title> <p>Gastric cancer remains a major cause of cancer-related mortality, and ferroptosis has emerged as a therapeutically exploitable vulnerability in malignant cells. However, the upstream regulators that sustain ferroptosis resistance in gastric cancer remain incompletely defined. Here, we identify KIF24 as a previously unrecognized regulator of ferroptosis resistance in gastric cancer. Inte...

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Literature Corpus work: 5ae3604f-b8e1-5cbb-8941-74a1565f5397
DOI: 10.21203/rs.3.rs-10011659/v1

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