Article

TRIM13 reduces damage to COPD alveolar epithelial cells by inhibiting ER-phagy induced by ERS

2024-08-18

Abstract excerpt

<title>Abstract</title> <p><bold>objective</bold> Exploring the molecular mechanisms by which tripartite motif-containing protein 13 (TRIM13) regulates alveolar epithelial cell injury in Chronic Obstructive Pulmonary Disease (COPD) provides new molecular targets for the treatment of COPD. <bold>Method</bold>Determining the expression levels of TRIM13 in clinical patients and in a rat model of emphysema. Construct...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5ac2e906-b180-5a4b-b9cd-1f5e5a5e97b8
DOI: 10.21203/rs.3.rs-4767755/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

TRIM13 reduces damage to COPD alveolar epithelial cells by inhibiting ER-phagy induced by ERSDOI 10.21203/rs.3.rs-4767755/v1Read

TRIM13 inhibits cell proliferation and induces autophagy in lung adenocarcinoma by regulating KEAP1/NRF2 pathwaySemantic proximity Read

TRIM13 regulates ER stress induced autophagy and clonogenic ability of the cellsSemantic proximity Read

TRIM31: A molecule with a dual role in cancerSemantic proximity Read

TRIM14 is a Putative Tumor Suppressor and Regulator of Innate Immune Response in Non-Small Cell Lung CancerSemantic proximity Read

MiR-4458 Regulates Autophagy and Apoptosis By Targeting P53 In Chronic Obstructive Pulmonary Disease.Semantic proximity Read

Mitochondrial dysfunction and impaired DNA damage repair through PICT1 dysregulation in alveolar type II cells in emphysemaSemantic proximity Read

Knockdown of RTEL1 Alleviates Chronic Obstructive Pulmonary Disease by Modulating M1, M2 Macrophage Polarization and InflammationSemantic proximity Read

TRIM59 Promotes the Proliferation and Migration of Non-Small Cell Lung Cancer Cells by Upregulating Cell Cycle Related ProteinsSemantic proximity Read

Role of Cigarette Smoke–Induced Aggresome Formation in Chronic Obstructive Pulmonary Disease–Emphysema PathogenesisSemantic proximity Read

Loss of Pleckstrin homology like domain, family A, member 1 promotes type Ⅱ alveolar epithelial cell apoptosis in chronic obstructive pulmonary disease emphysematous phenotype via interaction with tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon.Semantic proximity Read

miRNA-486-5p Promotes COPD Progression by Targeting HAT1 to Regulate the TLR4-Triggered Inflammatory Response of Alveolar MacrophagesSemantic proximity Read

TRIM59 as a novel molecular biomarker to predict the prognosis of patients with NSCLCSemantic proximity Read