Article

Leveraging multimodal neuroimaging and GWAS for identifying modality-level causal pathways to Alzheimer’s disease

2025-03-03

Abstract excerpt

The UK Biobank study has produced thousands of brain imaging-driven phenotypes (IDPs) collected from more than 40,000 genotyped individuals so far, facilitating the investigation of genetic and imaging biomarkers for brain disorders. Motivated by efforts in genetics to integrate gene expression levels with genome-wide association studies (GWASs), recent methods in imaging genetics adopted an instrumental variable...

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Literature Corpus work: 5a968bff-1147-5459-bbfb-2dd29e62e27d
DOI: 10.1101/2025.02.27.25322897

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