Article
Probabilistic Modeling of Imaging, Genetics and Diagnosis.
IEEE transactions on medical imaging - 1 Jul 2016
Batmanghelich Nematollah K, Dalca Adrian, Quon Gerald, Sabuncu Mert, Golland Polina
Abstract excerpt
We propose a unified Bayesian framework for detecting genetic variants associated with disease by exploiting image-based features as an intermediate phenotype. The use of imaging data for examining genetic associations promises new directions of analysis, but currently the most widely used methods make sub-optimal use of the richness that these data types can offer. Currently, image features are most commonly...
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