Article

<i>Plat</i> safeguards maternally aged oocytes against programmed cell death through activating the Erk1/2 pathway

2025-02-11

Abstract excerpt

<h4>ABSTRACT</h4> The decline in oocytes quality and developmental potential with female reproductive aging is well recognized, yet the underlying mechanisms remain insufficiently investigated. In this study, through an integrative analysis of transcriptomes and morphologies of individual oocytes from young and aged mice, morphologically defective aged oocytes are identified with distinct transcriptomic features....

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Literature Corpus work: 5a811995-1f19-5aa4-87bb-5b635223f866
DOI: 10.1101/2025.02.11.637629

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