Article

Transcriptome analysis of liver sinusoidal endothelial cells in patients with liver cirrhosis

2023-06-20

Abstract excerpt

<title>Abstract</title> <p>Background & Aims: Liver sinusoidal endothelial cells (LSECs) constitute the wall of the hepatic sinusoids, which are the first to be affected by various injuries and play an important role in the occurrence and development of chronic liver diseases caused by different etiologies. Using a combination of bulk RNA sequencing (bulk RNA-seq) and single-cell RNA sequencing (scRNA-seq) techni...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5a645905-a117-5c86-8597-211980ac7fb2
DOI: 10.21203/rs.3.rs-3027266/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptome analysis of liver sinusoidal endothelial cells in patients with liver cirrhosisDOI 10.21203/rs.3.rs-3027266/v1Read

Decoding liver fibrogenesis with single-cell technologiesSemantic proximity Read

Single-cell RNA sequencing advances in revealing the development and progression of MASH: the identifications and interactions of non-parenchymal cellsSemantic proximity Read

A Single Cell Gene Expression Atlas of 28 Human LiversSemantic proximity Read

A Human Liver Cell Atlas: Revealing Cell Type Heterogeneity and Adult Liver Progenitors by Single-Cell RNA-sequencingSemantic proximity Read

Single-cell transcriptomics reveals zone-specific alterations of liver sinusoidal endothelial cells in cirrhosisSemantic proximity Read

Single-Cell Transcriptomic Landscape of Intrahepatic B Cells in NASHSemantic proximity Read

Single-cell and bulk transcriptomics of the liver reveals potential targets of NASH with fibrosisSemantic proximity Read

Resolving the fibrotic niche of human liver cirrhosis using single-cell transcriptomicsSemantic proximity Read

The evolving role of liver sinusoidal endothelial cells in liver health and diseaseSemantic proximity Read

Intrahepatic transcriptomics differentiate advanced fibrosis and clinical outcomes in adults with the Fontan circulationSemantic proximity Read

Discovery of Endothelial–Monocyte Crosstalk in Ischemic‐Reperfusion Injury Following Liver Transplantation Based on Integration of Single‐Cell RNA and Transcriptome RNA SequencingSemantic proximity Read

RISING STARS: Liver sinusoidal endothelial transcription factors in metabolic homeostasis and diseaseSemantic proximity Read