Article

Exploration of Dark Chemical Genomics Space via Portal Learning: Applied to Targeting the Undruggable Genome and COVID-19 Anti-Infective Polypharmacology

2021-12-01

Abstract excerpt

<title>Abstract</title> <p>Advances in biomedicine are largely fueled by exploring uncharted territories of human biology. Machine learning can both enable and accelerate discovery, but faces a fundamental hurdle when applied to unseen data with distributions that differ from previously observed ones—a common dilemma in scientific inquiry. We have developed a new deep learning framework, called Portal Learning, t...

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Literature Corpus work: 5a1e0a85-a611-5679-aa4d-ff06ff3d58d2
DOI: 10.21203/rs.3.rs-1109318/v1

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